The singer mourned her son in a social media post on Wednesday.
“Today I joined the hundreds of thousands of families who lost loved ones due to opiate addiction,” Etheridge wrote on Twitter. “My son Beckett, who was only 21, struggled to overcome his addiction and eventually succumbed today. We will miss those who loved him, his family and friends.”
He added: “My heart is broken.”
A previous post on his social media accounts announced the postponement of the popular concert series Concerti da casa.
In his post, Etheridge assured, however, “I will sing again soon, it has always healed me.”
Etheridge also has twins with former partner Tammy Lynn Michaels, who gave birth in 2006.
Etheridge is now married to the television executive Linda Wallem.
“I am grateful for those who have reached condolences and feel their love and sincere pain,” added Etheridge in his post. “We struggle with what else we could have done to save him and in the end we know he is now out of pain.”